Injections raise serious risk, reveal shocking side effects dangerous for seniors

If you’ve been keeping an eye on the latest health trends, you’ve probably heard about the so-called 'fat jabs'—weight-loss injections like Ozempic, Wegovy, and Mounjaro.

These medications, known as GLP-1 agonists, have been hailed as a game-changer for people struggling with obesity, with some clinical trials showing users can lose up to 20 per cent of their body weight.

But before you rush to your GP to ask about them, there’s a new warning that’s especially important for our community of over-60s: these drugs may come with a hidden and potentially dangerous side effect.


While the promise of rapid weight loss is tempting, doctors are now raising the alarm about what you might be losing along with the fat.

According to the Royal Osteoporosis Society (ROS), up to 40 per cent of the weight lost on these injections isn’t just fat—it’s also vital muscle and bone mass.


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Doctors issued warnings that weight-loss injections may raise the risk of osteoporosis and fractures in the elderly. Credit: imyskin / iStock


For older Australians, this is particularly concerning.

Losing muscle can make you weaker and less steady on your feet while losing bone density increases your risk of osteoporosis—a condition that makes bones brittle and much more likely to break.

As we age, our bones naturally become less dense, and our muscles shrink unless we actively work to maintain them.


Add a medication that accelerates this process, and you could be looking at a recipe for falls, fractures, and a loss of independence.

As we get older, our bodies are already fighting an uphill battle against muscle and bone loss.

Women, in particular, are at higher risk of osteoporosis, especially after menopause when oestrogen levels drop and bone loss speeds up.

For those who are already frail or have a history of fractures, the risks are even greater.

Professor Carl Heneghan from Oxford University’s Centre for Evidence-Based Medicine put it bluntly: 'Any drug that reduces muscle mass and bone density is a bad idea for people who are frail and those vulnerable to fractures with osteoporosis.

The evidence is clear—these drugs carry significant risks, and the longer a patient stays on them, the greater the risk.'


With half a million people in the UK already taking these drugs (and numbers rising in Australia, too), it’s crucial to weigh the benefits against the risks.

While losing weight can certainly improve health outcomes for many, it’s not a one-size-fits-all solution—especially for older adults.

Dr Taher Mahmud, founder of the London Osteoporosis Clinic, emphasises the importance of a balanced diet and weight-bearing exercise for individuals considering or already taking GLP-1 agonists.

'It is essential that those taking GLP-1 agonists know about the importance of good nutrition and weight-bearing exercise,' he said.

This means making sure you’re getting enough protein, calcium, and vitamin D and staying active with activities like walking, gardening, or even light resistance training.

If you’re considering fat jabs, it’s important to speak with your doctor first—especially if you have a history of osteoporosis, fractures, or muscle weakness.


Ask how the injection might affect your bones and muscles and whether a bone density scan is recommended.

Support your body by eating a nutrient-rich diet and staying active with weight-bearing and resistance exercises.

If you experience new aches, pains, or weakness, report them to your doctor without delay.

Experts like Professor Heneghan argue that the focus should be on preventing obesity in the first place rather than relying on medications as a 'quick fix.'

For many, lifestyle changes—like eating a balanced diet, staying active, and maintaining a healthy weight—are still the safest and most effective way to protect your health as you age.

Remember, your health is your wealth—so let’s look after our bones and muscles as well as our waistlines!
Key Takeaways
  • Doctors are warning that using weight-loss injections such as Ozempic, Wegovy, and Mounjaro could increase the risk of osteoporosis and bone fractures, especially in the elderly and frail.
  • Research shows up to 40 per cent of the weight lost from these fat jabs comes from vital muscle and bone mass, not just fat.
  • Experts stress the importance of discussing the risks with a doctor, as losing muscle and bone can impair strength, stability, and independence—particularly for women and those already at risk of osteoporosis.
  • Maintaining good nutrition and doing weight-bearing exercise is essential for anyone taking GLP-1 agonists to help protect muscle and bone health.
Have you or someone you know tried these weight-loss injections? Did you notice any changes in your strength or bone health? Are you worried about the risks, or do you think the benefits outweigh them? We’d love to hear your experiences and thoughts in the comments below.
 

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I've lost almost 20 kg since September last year. Not using pills, potions, or injections or a certain style of dieting like gluten free or low carb. I counted calories and weighed food for a couple of months and then decided I'd learned enough to know what to do to go it alone. I've lost most of my weight eating sensibly and healthier without being fanatical about any food group. I feel much better, can get up off the floor without too much difficulty and do a little exercise 6 days a week.
 
I've lost almost 20 kg since September last year. Not using pills, potions, or injections or a certain style of dieting like gluten free or low carb. I counted calories and weighed food for a couple of months and then decided I'd learned enough to know what to do to go it alone. I've lost most of my weight eating sensibly and healthier without being fanatical about any food group. I feel much better, can get up off the floor without too much difficulty and do a little exercise 6 days a week.
Well done you! That's the way to do it. It's a lifestyle for you now & it's a great outcome for you. It's amazing how much better we feel with a good diet. 👍 👌👏🏻
 
I cannot fathom how anyone can inject themselves with this stuff only to lose weight!! Unless you have a life threatening disease of course & no other options. Obese individuals have options & no. 1 is a healthy lifestyle! Diets don't work. That's just yo yoing up & down. Neither do drinking these "shakes" they advertise. What happens when u stop drinking the shakes? You can't stay on them yr whole life. You may lose weight injecting this stuff into yr body but why risk getting all these other issues. And some are life threatening by the sounds of it. Crazy!!!
 
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Reactions: CemisugO
I agree that taking these drugs to lose weight is not a wise choice. Healthy eating along with regular exercise is the key to lose and maintain a good weight. I’m 75yrs old and have been eating healthy and working out with weights for over 40yrs and it’s paid off!
I’m 157cm tall and weight 55kilos..I don’t believe in diets as it’s a a choice of eating healthy foods or junk, and weight loss is 85% diet.. who knows what these drugs do in the long run…unless a person has honestly tried everything else, then these drugs should not, and need not to be taken…
 
I've lost almost 20 kg since September last year. Not using pills, potions, or injections or a certain style of dieting like gluten free or low carb. I counted calories and weighed food for a couple of months and then decided I'd learned enough to know what to do to go it alone. I've lost most of my weight eating sensibly and healthier without being fanatical about any food group. I feel much better, can get up off the floor without too much difficulty and do a little exercise 6 days a week.
Well done. Congratulations.
 
Ozempic is for type 2 diabetics 🩸🩸🩸. People who don't have diabetes should cut down on the bad boy carbs, like wheat products, fruit juices, soft drinks, pastas, rice, cakes, lollies, chips, potatoes, etc. The more bad boy carbs they eat, the fatter they get. Here is a link to all foods and how many carbohydrates they have. https://www.fatsecret.com.au/#search-food
So correct. The problem is most overweight people with bad diets end up with type 2 diabetes & qualify for the injection. If you change your lifestyle & what you are putting in your gut (unhealthy inflammatory foods) you can reverse the diabetes. It's very simple but obviously too hard for some people. They usually have been brought up in an unhealthy lifestyle & that's all they know. Education is so important when it comes to a healthy lifestyle.
 
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Reactions: Rickcb63
No such thing as a magic weight loss. There will always be nasty side effects when you are using a drug which is made for a particular illness. Then it is used for a completely different issue.
Just love who you are. Better to accept your body than putting your health at risk.
Best wishes to all
 
If you’re serious about weight loss then wire your bloody jaw shut?
It’s not always food,, my medication causes weight gain, I don’t actually eat much at all, I don’t drink, or smoke, and I’m normally around 110, yes solid build, but medication has taken me to 124, and can only do walking for exercise, and can’t do long walks, backs buggered, neck the same bad arthritis in lower spine and severe neuropathy in my legs with loss of feeling.
My cardiologist last week offered Ozempic , as it’s been a struggle, but I wanted to find out more about it..
 
Certain prescribed medications also cause weight gain such as insulin, anti psychotics, anti depressants, anti convulsants and mood stabilisers.

Unfortunately, some people don't have a choice and it's not all about food.
So true Veggiepatch. Most of us don't choose to carry extra weight. Many of us don't have a choice. Some are very quick to judge. Oh you are overweight you must sit around all day eating all the wrong foods and don't exercise. Not always the case.
 
Ozempic is for type 2 diabetics 🩸🩸🩸. People who don't have diabetes should cut down on the bad boy carbs, like wheat products, fruit juices, soft drinks, pastas, rice, cakes, lollies, chips, potatoes, etc. The more bad boy carbs they eat, the fatter they get. Here is a link to all foods and how many carbohydrates they have. https://www.fatsecret.com.au/#search-food
It’s not just for type 2 diabetics !
 
It’s not always food,, my medication causes weight gain, I don’t actually eat much at all, I don’t drink, or smoke, and I’m normally around 110, yes solid build, but medication has taken me to 124, and can only do walking for exercise, and can’t do long walks, backs buggered, neck the same bad arthritis in lower spine and severe neuropathy in my legs with loss of feeling.
My cardiologist last week offered Ozempic , as it’s been a struggle, but I wanted to find out more about it..
At least you are walking. I totally understand where you are coming from. Just keep up the clean living, walking. I have a lot of similar health issues but go for a walk every day with the help of a walker. Just keep doing the best you can. Best of health to you.
 
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Reactions: Rickcb63
It’s not always food,, my medication causes weight gain, I don’t actually eat much at all, I don’t drink, or smoke, and I’m normally around 110, yes solid build, but medication has taken me to 124, and can only do walking for exercise, and can’t do long walks, backs buggered, neck the same bad arthritis in lower spine and severe neuropathy in my legs with loss of feeling.
My cardiologist last week offered Ozempic , as it’s been a struggle, but I wanted to find out more about it..
Lucky us said.
That comment is really not helpful or very nice
 
Lucky us said.
That comment is really not helpful or very nice
Our illustrious medicinal profession stuffed me royally putting on steroids and causing an twenty odd kilo weight gain that did and is stll wanders for my continued ill health FUB didn't check my medication? Also I don't give a toss whether your offended regarding what I considered a light dig , get a life>
 

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