Are acid reflux medications increasing your risks of dementia? Find out now!
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When visiting the doctor, it's quite common to hear them recommend medications for all kinds of illnesses. For acid reflux or gastroesophageal reflux disease (GERD), the standard treatment is a type of drug called proton pump inhibitors.
Proton pump inhibitors like Nexium, Pariet, Losec, Somac, and Zoton block stomach acid production, reducing inflammation and healing ulcers caused by acid.
But what if taking these medications for too long could increase your chance of developing dementia?
A study was published in Neurology, the medical journal of the American Academy of Neurology, which investigated the connection between taking proton pump inhibitors and the risk of dementia.
The study recruited 5,712 people who didn't have dementia, aged 45 and above, with an average age of 75.
The team divided the participants into different groups based on how long they took the medications for and calculated the number of individuals and how long they were in the study (‘person-years’).
In the medication-free group, 19 cases of dementia per 1,000 person-years were reported.
As for those who took the drugs for more than 4.4 years, the rate of dementia was 24 cases per 1,000 person-years.
After adjusting the data for demographic and health-related factors, the researchers were able to show that those taking proton pump inhibitors had a 33% higher risk of dementia than those who didn't take the medications.
So how worrisome is this news?
It's important to note that this study did not prove that proton pump inhibitors cause dementia.
Aside from the fact that there are many other factors that contribute to the condition, the study had some limitations, such as determining the participants’ proton pump inhibitor intake through annual check-ins and not knowing whether they took other drugs as well.
The study author, Kamakshi Lakshminarayan, MBBS, PhD, concluded: ‘More research is needed to confirm our findings and explore reasons for the possible link between long-term proton pump inhibitor use and a higher risk of dementia.’
Still, if you're currently taking these medications, it's a good idea to speak to your doctor about your risk of dementia.
Moreover, it would be useful to consider other approaches to treat acid reflux, so you can make an informed decision on which option is best for you.
‘While there are various ways to treat acid reflux, such as taking antacids, maintaining a healthy weight, and avoiding late meals and certain foods, different approaches may not work for everyone,’ Lakshminarayan adds.
He concluded, ‘It is important that people taking these medications speak with their doctor before making any changes, to discuss the best treatment for them, and because stopping these drugs abruptly may result in worse symptoms.’
Whatever you choose, we hope you find relief from acid reflux soon!
What are your thoughts on this research? Do you have any go-to advice on how to relieve acid reflux? Share your thoughts with us in the comments below!
Proton pump inhibitors like Nexium, Pariet, Losec, Somac, and Zoton block stomach acid production, reducing inflammation and healing ulcers caused by acid.
But what if taking these medications for too long could increase your chance of developing dementia?
The study recruited 5,712 people who didn't have dementia, aged 45 and above, with an average age of 75.
The team divided the participants into different groups based on how long they took the medications for and calculated the number of individuals and how long they were in the study (‘person-years’).
In the medication-free group, 19 cases of dementia per 1,000 person-years were reported.
As for those who took the drugs for more than 4.4 years, the rate of dementia was 24 cases per 1,000 person-years.
After adjusting the data for demographic and health-related factors, the researchers were able to show that those taking proton pump inhibitors had a 33% higher risk of dementia than those who didn't take the medications.
So how worrisome is this news?
It's important to note that this study did not prove that proton pump inhibitors cause dementia.
Aside from the fact that there are many other factors that contribute to the condition, the study had some limitations, such as determining the participants’ proton pump inhibitor intake through annual check-ins and not knowing whether they took other drugs as well.
The study author, Kamakshi Lakshminarayan, MBBS, PhD, concluded: ‘More research is needed to confirm our findings and explore reasons for the possible link between long-term proton pump inhibitor use and a higher risk of dementia.’
Moreover, it would be useful to consider other approaches to treat acid reflux, so you can make an informed decision on which option is best for you.
‘While there are various ways to treat acid reflux, such as taking antacids, maintaining a healthy weight, and avoiding late meals and certain foods, different approaches may not work for everyone,’ Lakshminarayan adds.
He concluded, ‘It is important that people taking these medications speak with their doctor before making any changes, to discuss the best treatment for them, and because stopping these drugs abruptly may result in worse symptoms.’
Key Takeaways
- Proton pump inhibitors, used for treating acid reflux or gastroesophageal reflux disease (GERD), may increase dementia risk when taken for more than 4.5 years.
- The study was published in Neurology, and involved 5,712 participants who did not have dementia, with those taking the medication for more than 4.4 years showing a higher rate of dementia.
- Despite the findings, limitations of the study included the determination of participants’ proton pump inhibitor intake through annual check-ins and lack of knowledge on whether participants took other over-the-counter antacids or reflux medications.
- Alternatives to acid reflux medications include lifestyle changes and natural remedies, however, before stopping proton pump inhibitors or taking any alternative acid reducers, patients are advised to talk with a healthcare provider.
Whatever you choose, we hope you find relief from acid reflux soon!
What are your thoughts on this research? Do you have any go-to advice on how to relieve acid reflux? Share your thoughts with us in the comments below!