Experts reveal shocking dangers of long-term antidepressant use in seniors

It’s no secret that mental health is as important as physical health—especially as we age.

But a new warning from medical experts has many Australians over 60 (and their families) asking: are we doing enough to protect our seniors from the hidden dangers of long-term antidepressant use?


Recent reports have revealed that thousands of older Australians are being left on antidepressant medications for years—sometimes even decades—without regular reviews or consideration of safer alternatives.

While these medications can be life-changing for those struggling with depression, experts are now raising the alarm about the potential risks of staying on them for too long, particularly in our senior years.

Did you know that more than one in five Australians over 65 are now taking antidepressants?


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Thousands of older Australians have been kept on antidepressants for decades, raising concerns about memory loss and dangerous falls. Credit: Savushkin / iStock


That’s more than double the rate from just 20 years ago!

While this may reflect greater awareness and willingness to seek help for mental health issues, it also raises important questions about whether we’re relying too heavily on medication—especially when it comes to our older population.

As we age, our bodies process medications differently, and the side effects of antidepressants can become more pronounced.


Some of the most common antidepressants, known as selective serotonin reuptake inhibitors (SSRIs), work by increasing levels of serotonin in the brain—a chemical linked to mood.

While generally safe for most people, these medications can cause side effects such as dizziness and unsteadiness, nausea, agitation or restlessness, loss of libido, erectile dysfunction (in men), and memory problems.

For seniors, these side effects can be more than just uncomfortable—they can be dangerous.

Dizziness, for example, significantly increases the risk of falls, which can lead to life-threatening fractures or hospitalisations.

Memory issues can also be mistaken for dementia, causing unnecessary worry and confusion for families.

It’s not just the side effects that cause concern. Many older adults who try to stop taking antidepressants experience withdrawal symptoms, including trouble sleeping, mood swings, and restlessness.


This can make it difficult for patients to come off the medication, even if they no longer need it for their mental health.

Take the case of Heather Hicks, a 76-year-old who has been on antidepressants since 1996.

She’s tried to stop taking them three times, but withdrawal symptoms have always forced her to start again.

'I wish the GP had suggested counselling rather than prescribing a drug that is so difficult to stop,' she says.

Experts say there are several reasons why older Australians are staying on these medications for years:

Many older adults continue taking medications without proper review, as GPs often renew prescriptions without reassessing their necessity.

Although talking therapies like counselling or group sessions are considered safer alternatives, especially for seniors, limited availability and long wait times mean these options are often out of reach.


Compounding the issue, depression in older adults is frequently tied to loneliness and social isolation—factors that medication alone can't fully address.

Experts stress that meaningful social support plays a critical role in recovery yet remains difficult for many to access.

Professor Robert Howard, an expert in old age psychiatry, says: 'We know that there are patients who have been on antidepressants for a very long time, who perhaps no longer need them. It’s crucial that GPs identify these patients and help them come off the medication safely.'

Antidepressants can be a vital lifeline for many people, including seniors. But like all medications, they need to be used carefully and reviewed regularly—especially as we age.

If you’re concerned about your medication or that of a loved one, don’t hesitate to speak up and ask questions.
Key Takeaways
  • Thousands of older Australians have been left on antidepressants for decades, raising concerns about risks such as memory problems and potentially life-threatening falls.
  • More than one in five people over 65 are now taking antidepressants—more than double the number from twenty years ago.
  • Experts warn that GPs may be allowing elderly patients to stay on these medications indefinitely, often without reviewing their need for them or offering safer alternatives like counselling.
  • Antidepressants can cause more complications as patients age, and older people are less likely to be offered talking therapies due to long NHS waiting lists and under-referral, increasing reliance on medication.
Have you or someone you know been on antidepressants for a long time? What has your experience been like? Do you think there are enough alternatives available for seniors? Share your thoughts and stories in the comments below.
 

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What alternatives are there?
We went to a clinical psychologist for a few years.talk fest.no decent outcomes.
One of his suggestions was to start breeding reptiles...well how not helpful is that..I hate reptiles
The article mentions SSRIs the alternatives to them are any one of the other four types of antidepressants, they all work differently on different neurotransmitters /hormones and may work better for some people. There is no hard and fast rules with these drugs, hence you may need to try different ones over many months to see which fits best for you in regards to affects and side effects.
 
The article mentions SSRIs the alternatives to them are any one of the other four types of antidepressants, they all work differently on different neurotransmitters /hormones and may work better for some people. There is no hard and fast rules with these drugs, hence you may need to try different ones over many months to see which fits best for you in regards to affects and side effects.
The antidepressant Agomelatine is much better as it does not have the side effects of SSRIs , with no withdrawal syndrome. It can affect the liver, however we monitor for that with regular blood tests. The liver affect is usually in patients who already have liver problems. It works through the Dopamine pathway. Unfortunately the government won't list it on the PBS. I think this is mainly due to cost. It costs the patient from $45 to $70 per month, with some cover through private extra cover.
That said, there are many patients who need long term SSRIs to function. They just need regular monitoring, Blood tests to monitor for sodium levels, which may cause confusion. Withdrawal of SSRIs should be done very gradually, and we need more low dose versions to allow this.
 
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The antidepressant Agomelatine is much better as it does not have the side effects of SSRIs , with no withdrawal syndrome. It can affect the liver, however we monitor for that with regular blood tests. The liver affect is usually in patients who already have liver problems. It works through the Dopamine pathway. Unfortunately the government won't list it on the PBS. I think this is mainly due to cost. It costs the patient from $45 to $70 per month, with some cover through private extra cover.
That said, there are many patients who need long term SSRIs to function. They just need regular monitoring, Blood tests to monitor for sodium levels, which may cause confusion. Withdrawal of SSRIs should be done very gradually, and we need more low dose versions to allow this.
As I said, some work well for one and not another, they ALL have side effects to different degrees and dependent on the person.
 
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As I said, some work well for one and not another, they ALL have side effects to different degrees and dependent on the person.
Yes of course, but I feel that Agomelatine should be listed on PBS. I have seen great results with this drug.
 
Iv'e been on Zoloft 200mb for 20+ years.
I have tried to ween myself off of it over the years but it didn't work.
Before I started taking it my doctor sent me to a psychologist, after several sessions she came to realise that I didn't want to change, and that I needed something to stabalize my moods, hense the Zoloft..
 
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I have been on the same antidepressant for 25 years. Sometimes l have to increase the dosage, from time to time. Then l drop back to my normal dosage. I have tried a couple of times to cut back. Oh no not a good idea. I don't think l would be here if l wasn't on my meds. I should have been on them years before.
I have been to phycologhist and had physiotherapy for two years. That helped me greatly. I still struggle greatly with mental health issues mainly due to family issues. The one side affect l believe is weight gain. Lucky for me the only other meditation l take is reflux medication due to a lung condition and one antibiotic a day to keep chest infections at bay and Panadol Osteo and inhalers for my lung condition. So at 62 l suppose l am lucky not be on a lot of meditation that could interact with the antidepressants.
I will be on the mad pills forever to keep me sane.
Kind regards to all Vicki
 
This is definitely an important topic. While antidepressants can be helpful, it's true that long-term use—especially in older adults—should be closely monitored. I think it’s crucial for seniors and their families to stay informed and regularly consult with healthcare professionals to weigh the risks and benefits. Mental health matters, but so does safety.


Thanks for sharing this—it really makes you think.
 
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Hi I've been taking citalipram for over 30 years. In the beginning I tried many different sorts and found this the best suited to me...5 times I have tried to come off them, but fell into a heap each time. Have also tried specialists and even hypnotherapy. Nothing could help.. both my adult children take antidepressants and they are on different chemical compounds to mine. I asked Dr if it can be hereditary and the answer was if it's caused by a chemical imbalance then yes, if it caused through a live event then no.. It used to be frowned upon, even my own father told me it was all in my head and I needed to pull my socks up and just get on with life... for some that is not possible .. and if taking 1 small tablet a day for the rest of my life, it's better than the alternative.. suicide.. I know what I would rather..
 
Hi I've been taking citalipram for over 30 years. In the beginning I tried many different sorts and found this the best suited to me...5 times I have tried to come off them, but fell into a heap each time. Have also tried specialists and even hypnotherapy. Nothing could help.. both my adult children take antidepressants and they are on different chemical compounds to mine. I asked Dr if it can be hereditary and the answer was if it's caused by a chemical imbalance then yes, if it caused through a live event then no.. It used to be frowned upon, even my own father told me it was all in my head and I needed to pull my socks up and just get on with life... for some that is not possible .. and if taking 1 small tablet a day for the rest of my life, it's better than the alternative.. suicide.. I know what I would rather..
Well said. I could not agree more with you. My brother sister and l all are on what we loving call mad pills. It comes from my father's side of the family. Who cares. No one questions or judges you when you have life threatening illness. What some don't understand is anxiety and depression can be life threatening illness. Keep taking your little pill each day and give up trying to come off them. We are what we are.
Keep well my dear. Kind regards Vicki
 

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